For decades, scientists have focused on amyloid beta as a major culprit behind Alzheimer’s disease, spending billions of dollars developing treatments that have often delivered disappointing results. Now, researchers at UC Santa Cruz are drawing attention to a largely overlooked peptide called P3 that could also play a role in the disease. Previously believed to be harmless, P3 can form harmful-looking protein clumps even faster than amyloid beta and may also damage brain cells.
Scientists may have solved a long-standing mystery about why the Moon’s two sides are so different, using samples collected from its farside for the first time. Their findings suggest that uneven heating from Earth's gravitational pull drove enormous flows of ancient magma, creating the dramatically different lunar landscapes we see today.
Scientists have discovered a protein that may help harmful aging cells hide from the immune system, allowing them to accumulate and fuel age-related health problems. Blocking the protein in mice reduced these cells and inflammation while improving blood sugar regulation and strength, offering a promising new direction for anti-aging research.
A massive prehistoric snake discovered in India may have rivaled the largest snake ever known. Called Vasuki indicus, the 47-million-year-old giant could have reached up to 50 feet long, making it comparable to the legendary Titanoboa. Scientists believe its enormous body made it a slow-moving ambush predator, similar to a modern anaconda.
A new study reveals that people draw a surprisingly sharp line between human consciousness and artificial intelligence, even when both behave identically. Researchers found that participants considered even the most responsive AI less conscious than the least responsive human. Yet when asked about "awareness" instead, people judged humans and AI much more similarly.
Astronomers have discovered that a scorching-hot planet 320 light-years away shares a striking chemical similarity with its host star, providing the first direct evidence for a fundamental assumption about planet formation. The breakthrough could help scientists predict what distant rocky planets are made of and identify worlds with conditions favorable for life.
Scientists used artificial intelligence to uncover nearly 10,000 chemical reactions involved in transforming carbon dioxide into fuels and chemicals, revealing crucial pathways that traditional models had missed. The discovery dramatically improved predictions of CO2 conversion and uncovered a surprising hydrogen reaction that could inspire more efficient catalysts.
A newly identified 210-million-year-old dinosaur from Zimbabwe is helping scientists uncover a surprisingly distinct prehistoric ecosystem. The discovery suggests that ancient climate differences may have separated dinosaur populations across southern Africa, leading to unique species that challenge previous assumptions about their evolution.
NASA’s James Webb Space Telescope has revealed an ancient galaxy cluster with an unexpectedly dense concentration of dark matter, challenging theories about how the universe developed. The discovery also uncovered a surprising connection between scattered starlight and invisible dark matter that could transform how astronomers study the early cosmos.
A 165-million-year-old fossil has revealed an extraordinary Jurassic predator that may help explain how mammals developed one of their most important evolutionary advantages. Although only 20 inches long, Megacauda sungei was a heavyweight among early mammal relatives, swimming through ancient waterways and hunting prey with specialized teeth. Its advanced swallowing anatomy reveals an early step toward the ability to safely nurse on milk, a key development in mammalian evolution.
Scientists have traced the development of a mouse embryo from its first two cells to the formation of organs, using a remarkable DNA recording system that reveals the family history of individual cells. Their findings uncover how different cell types emerge on their own schedules and could help explain what goes wrong in birth defects, genetic disorders, and cancer.
Oxford physicists have recreated a bizarre quantum effect in which a particle responds to a magnetic field without ever traveling through it. Using a hybrid quantum computer, they demonstrated how introducing a simulated magnetic flux could completely halt a particle's movement through quantum interference. The experiment brings a decades-old prediction into a new setting where matter and quantum fields influence one another.
Scientists have uncovered a hidden layer of organization in the brain by creating the first detailed 3D map of its lipids, the fatty molecules essential for brain structure and communication. By analyzing millions of measurements from mouse brains, researchers identified 539 distinct chemical zones, revealing patterns and boundaries that traditional brain maps have missed. Surprisingly, even white matter, once thought to be relatively uniform, contains a complex patchwork of chemically distinct regions.
Scientists have uncovered a surprising hidden ability of light that allows it to develop spinning, twisting behavior as it travels through empty space, without special lenses, mirrors, or materials. Researchers discovered that light’s internal geometry can naturally produce left- and right-handed patterns, challenging long-standing assumptions about how light behaves. By carefully arranging a beam’s structure, scientists can control where and how these spinning patterns emerge, unlocking a new way to manipulate light.
Scientists have created a new coating for mitochondria that preserves their ability to produce energy, potentially opening the door to new treatments for diseases involving these tiny cellular powerhouses. The technology could one day help transfer healthy mitochondria into damaged cells, although its effectiveness in transplantation remains unproven.
Europe's Sentinel-3C satellite has returned breathtaking images of Earth just two weeks after launch, revealing the snowy Alps, frozen Arctic islands, and brilliant turquoise Caribbean waters. Its first measurements also show promising results for tracking rising seas, melting ice sheets, and other changes reshaping our planet.
Scientists may have solved a 2.3-billion-year-old mystery about how Earth maintained enough oxygen to support life. Ancient rocks reveal that phosphorus recycling in the oceans created a self-sustaining cycle that helped keep oxygen levels high, even as the planet underwent dramatic environmental changes. The discovery challenges assumptions about Earth's early atmosphere and raises new questions about why complex life took so long to emerge.
The remarkable intelligence of octopuses, squid, and cuttlefish may trace back to an ancient reshuffling of their DNA that created new connections between genes. Scientists discovered that these changes in the genome's 3D structure may have helped drive the evolution of their unusually complex nervous systems.
Researchers discovered a hidden factor that can determine whether chemical reactions succeed or fail, and then used it to boost the proportion of the desired product from 16% to 97%. By controlling acidity near electrodes, they developed a promising way to manufacture chemicals for plastics, medicines, and other products using oxygen and electricity instead of hazardous added oxidants.
Scientists have discovered that vanillin, the compound that gives vanilla its distinctive flavor, has powerful properties that could help fight infections, reduce inflammation, and promote wound healing. The inexpensive, widely available ingredient could one day become an important component of advanced wound treatments and regenerative medicine.