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Madonna is re-inventing what it means to be nakedly political in an eyebrow-raising post to her social media accounts Wednesday, in which she uses a nude photo to back Democratic presidential nominee Hillary Clinton.

Canada may have rolled out the red carpet for Prince William and Kate Middleton's visit, but that didn't stop the royal couple from being snubbed by some.

Not everyone is rejoicing following the birth of a seemingly healthy three-parent baby earlier this year, which is detailed in study published in a scientific journal Tuesday. The baby boy was born on April 6 in Mexico, having been conceived using a technique called spindle nuclear transfer.

Beloved internet meme Pepe the Frog has gone through various incarnations over the years, reflecting a range of emotions.

As Aleppo teeters on the brink of falling to Syrian regime forces, there is no consensus in the Obama administration on what, if any, action to take to help the beleaguered opposition with which the US is allied, several American officials have told CNN.

Shimon Peres, the Israeli elder statesman who shared a Nobel Prize for forging a peace deal between Israelis and Palestinians, has died.

Plenty of questions surround Tuesday's shooting death of a black man by police in Southern California -- a killing that authorities say happened after the man raised his hands in a threatening "shooting stance" toward an officer.

FBI Director James Comey isn't a weasel, he told lawmakers Wednesday.

A speeding car collided with a pole, split into pieces and tumbled across a popular walking trail. Everyone involved, including the driver, walked away uninjured.

It used to be that sex and offensive language were the most frequently cited reasons for attempts to remove books from schools and libraries. And, anything to do with Harry Potter.

Obama sits down with Jake Tapper and a military audience to talk about national security, veterans' issues and foreign policy challenges at 9 p.m. ET.

Malaysia Airlines Flight 17 was downed over eastern Ukraine by a Buk missile brought in from Russia and fired from a village under the control of pro-Russian separatists, a team of international prosecutors said Wednesday.

Malaysia Airlines Flight 17 was downed over eastern Ukraine by a Buk missile brought in from Russia to a pro-Russian area of eastern Ukraine, the head of the Dutch National Detective Force, Wilbert Paulissen said Wednesday.

Shortcomings at federal and state agencies allow sales of firearms to people prohibited from buying them, a Justice Department inspector general probe found.

Pete Rose isn't giving up on his quest to be inducted into the National Baseball Hall of Fame.

Colin Kapernick-style protests have migrated from the playing field to the classroom.

The Senate voted to override President Barack Obama's veto of a bill that would allow victims and families of 9/11 to sue Saudi Arabia for its alleged role in the terrorist attack 15 years ago.

Two hospitals in eastern Aleppo have been bombed "out of service", staff and activists said, as airstrikes continued to pound rebel-held parts of the city.

A Muslim-American journalist Noor Tagouri will appear in Playboy magazine's October issue wearing a hijab, a decision that has elicited praise in some quarters and provoked condemnation in others.

As Hillary Clinton on Monday night reeled off a litany of insults he had leveled against women through the years, including some nasty nicknames for a former Miss Universe, Donald Trump leaned into his microphone and asked repeatedly, "Where did you find this? Where did you find this?"