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Serena Williams will have to wait to become the first player in the Open Era to win 23 majors after she was upset in the US Open semis by Karolina Pliskova.

Serena Williams has been knocked from her No. 1 ranking by Czech 10th seed Karolina Pliskova, half of another tennis sister act.

Rather than a bargaining chip used to gain more foreign aid or access to the world stage, it appears that the country's nuclear weapons program boils down to a matter of dignity and national pride.

European security officials estimate that 30 to 40 suspected ISIS terrorists who helped support the November 13 Paris terror attacks are still at large, CNN has learned.

Uber's booming business in Lagos, Nigeria, has hit a major speed bump as the government has begun cracking down on drivers, requiring them to pay huge sums to register for special licenses.

Saudi Arabia is hoping religious tourists, including millions of Hajj pilgrims, could help plug a big hole in its budget.

Hillary Clinton will visit the National September 11 Memorial on Sunday, marking the 15th anniversary of the 2001 terrorist attack, according to an aide.

Twenty Marines have been identified for possible military justice or administrative discipline in the death of a recruit at Parris Island, South Carolina, the Marines said Thursday in a statement.

Weak global demand for food has pushed down the price of many key agricultural commodities such as corn and wheat. That's great news for consumers ... but it's awful news for Kroger, Whole Foods and other supermarket chains.

A Georgia police officer is accused of raping a woman while he was transporting her to a jail in an Atlanta suburb, state authorities say.

ITT Educational Services, which operates ITT Tech, announced it will be filing for bankruptcy protection.

Construction workers took a death-defying photo from atop a spire 1,099 feet above the ground in Los Angeles earlier this week.

North Korea has carried out its fifth nuclear test, and Kim Jong Un is smiling.

Fair Spirits, the first and only Fair Trade certified liquor company, sells luxury vodka, gin, rum and other spirits in dozens of countries.

Fewer households in the United States are going hungry, but many still struggle, a new government report reveals.

The U.S. Senate tipped off European authorities that Apple might be receiving illegal state aid from Ireland in the form of artificially low taxes.

Libertarian vice president nominee William Weld said Friday that he doesn't think running mate Gary Johnson's failure to identify the besieged Syrian city of Aleppo should disqualify him from being president.

NBC News knows the "Commander-in-Chief Forum" was not Matt Lauer's finest hour. Here's an inside look at what went wrong.

Gordon Reid may be looking to emulate fellow Scot Andy Murray in Rio but it's the Swiss maestro who the wheelchair tennis champion always looked up to.

Hillary Clinton spoke candidly in interviews published Thursday about perceptions that she can sometimes come off as "cold or unemotional," describing her struggle to control her emotions without seeming "walled off" and speaking in personal terms about what it's like to campaign as a woman.